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Article

Dynein-dynactin segregate meiotic chromosomes in C. elegans spermatocytes.

Development (Cambridge, England) - 10 Feb 2021

Barbosa Daniel J, Teixeira Vanessa, Duro Joana, Carvalho Ana X, Gassmann Reto

Abstract excerpt

The microtubule motor cytoplasmic dynein 1 (dynein) and its essential activator dynactin have conserved roles in spindle assembly and positioning during female meiosis and mitosis, but their contribution to male meiosis remains poorly understood. Here, we characterize the G33S mutation in the C. elegans dynactin subunit DNC-1, which corresponds to G59S in human p150Glued that causes motor neuron disease. In...

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Identifiers

PMID: 33462114
DOI: 10.1242/dev.197780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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