Article
Relationship between acetylator phenotype and intensity of the hypoglycaemic effect of a suplhonamide preparation in children with insulin-dependent diabetes.
Bratislavske lekarske listy - 1 Dec 1991
Hadasová E, Brysová V, Utĕsený J, Macků M
Abstract excerpt
The distribution of acetylator phenotypes was determined in 95 healthy children (4-15 y) and in 48 children with Type I diabetes (5-15) using the sulphadimidine test for the determination of acetylation capacity. The frequency of slow acetylators within the diabetic group (60.4%) closely resembled that in the healthy population (59.0%). There was no significant sex difference within either group. Subgrouping...
Topics
- Acetylation
- Adolescent
- Blood Glucose
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Female
- Humans
- Male
- Phenotype
- Sulfamethazine