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Article

Transfer of engineered biophysical properties between different antibody formats and expression systems.

Protein engineering, design & selection : PEDS - 1 Oct 2012

Schaefer Jonas V, Plückthun Andreas

Abstract excerpt

Recombinant antibodies and their derivatives are receiving ever increasing attention for many applications. Nevertheless, they differ widely in biophysical properties, from stable monomers to metastable aggregation-prone mixtures of oligomers. Previous work from our laboratory presented the combination of structure-based analysis with family consensus alignments as being able to improve the properties of...

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PMID: 22763265
DOI: 10.1093/protein/gzs039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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