Article
Increased Asymmetric and Multi-Daughter Cell Division in Mechanically Confined Microenvironments
25 Jun 2012
Abstract excerpt
As the microenvironment of a cell changes, associated mechanical cues may lead to changes in biochemical signaling and inherently mechanical processes such as mitosis. Here we explore the effects of confined mechanical environments on cellular responses during mitosis. Previously, effects of mechanical confinement have been difficult to optically observe in three-dimensional and in vivo systems. To address this...
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