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Article

Genomic imprinting: the influence of differential methylation in the two sexes

1 Feb 2010

Abstract excerpt

Genomic imprinting is an epigenetic form of gene regulation that entails differential sex-specific methylation of the alleles of a gene. Such methylation distinguishes male and female genomes and is inherited in a parent-of-origin-specific manner. Sex-specific imprints are established in the germline during gametogenesis and remain intact throughout embryonic and postnatal development. Reprogramming of...

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PMID: 20404028
DOI: 10.1258/ebm.2009.009251

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