Article
Polymorphisms in the melatonin receptor 1B gene and the risk of delirium.
Dementia and geriatric cognitive disorders - 1 Jan 2012
de Jonghe A, de Rooij S, Tanck M W T, Sijbrands E J G, van Munster B C V
Abstract excerpt
BACKGROUND/AIMS: A disturbed sleep-wake rhythm cycle can be seen in delirium and as melatonin regulates this cycle via melatonin receptors, genetic variations in these receptors may contribute to susceptibility to delirium. The purpose of this study was to investigate whether genetic variants in the melatonin receptor 1B (MTNR1B) gene are associated with delirium. METHODS: Elderly medical and hip surgery patients...
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