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Article

Causal association between sleep disorders and delirium: A bidirectional mendelian randomization analysis for clinical practice.

Archives of gerontology and geriatrics - 1 Feb 2026

Niu Wenxiu, Zhang Jingjing, Lan Xuhong, Sha Yuhan, Han Xiaomeng, Qiao Jijun, Zheng Fei, Liu Lu, Ma Fangli, Yao Li, Zhang Zhigang

Abstract excerpt

BACKGROUND: Numerous studies have identified a correlation between sleep disorders and delirium; however, the causal relationship remains ambiguous. This bidirectional two-sample Mendelian randomization (MR) study, combined with colocalization and enrichment analyses, aims to investigate the potential causal relationship between sleep-associated phenotypes and delirium. METHODS: We performed a two-sample...

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PMID: 41197553
DOI: 10.1016/j.archger.2025.106046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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