Article
KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients.
Scientific reports - 11 Jan 2022
Terrelonge Mark, LaHue Sara C, Tang Christopher, Movsesyan Irina, Pullinger Clive R, Dubal Dena B, Leung Jacqueline, Douglas Vanja C
Abstract excerpt
Despite the association between cognitive impairment and delirium, little is known about whether genetic differences that confer cognitive resilience also confer resistance to delirium. To investigate whether older adults without postoperative delirium, compared with those with postoperative delirium, are more likely to have specific single nucleotide polymorphisms (SNPs) in the FKBP5, KIBRA, KLOTHO, MTNR1B, and...
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