Article
Genetic polymorphisms in the DRD2, DRD3, and SLC6A3 gene in elderly patients with delirium.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2010
van Munster Barbara C, Yazdanpanah Mojgan, Tanck Michael W T, de Rooij Sophia E J A, van de Giessen Elsmarieke, Sijbrands Eric J G, Zwinderman Aeilko H, Korevaar Johanna C
Abstract excerpt
Dopamine excess appears to be critical in the final common pathway of delirium. The aim of this study was to investigate whether genetic polymorphisms in three dopamine-related genes (the dopamine receptor 2 (DRD2), dopamine receptor 3 (DRD3), and the dopamine transporter (SLC6A3) gene) were associated with delirium. Patients aged 65 years and older acutely admitted to the medical department or to the surgical...
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