Article
The Plowright vaccine strain of Rinderpest virus has attenuating mutations in most genes.
The Journal of general virology - 1 Apr 2005
Baron M D, Banyard A C, Parida S, Barrett T
Abstract excerpt
The currently used vaccine strain of Rinderpest virus was derived by serial passage of the highly virulent Kabete 'O' strain (KO). A full-length cDNA copy of the KO strain was made from which a virus identical in pathogenicity to the wild-type virus was rescued. A series of chimeric viruses was prepared in which the coding sequences for the N, P, F, H or L proteins were replaced with the corresponding sequences...
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