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Article

Assessment of protective efficacy of live and killed vaccines based on a non-encapsulated mutant of Streptococcus suis serotype 2.

Veterinary microbiology - 3 Jan 2002

Wisselink Henk J, Stockhofe-Zurwieden Norbert, Hilgers Luuk A T, Smith Hilde E

Abstract excerpt

The protective efficacy of a live and killed non-encapsulated isogenic mutant of Streptococcus suis serotype 2 was determined in pigs, and compared with the efficacy of the capsulated wild-type strain. SPF pigs were vaccinated twice intramuscularly at 4 and 7 weeks of age with a dose of 1 x 10(9) formalin-killed CFU of the wild-type (WT-BAC), formalin-killed non-encapsulated mutant (CM-BAC) or live...

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PMID: 11731168
DOI: 10.1016/s0378-1135(01)00452-7

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