Article
Attenuated live fowl cholera vaccine. I. Development of vaccine strain M3G of Pasteurella multocida.
Avian diseases - 1 Jan 2000
Hertman I, Markenson J, Michael A, Geier E
Abstract excerpt
A live cholera vaccine was developed from a virulent avian septicemia strain of Pasteurella multocida serotype 1. The virulent parental strain was mutagenized with N-methyl-N'-nitro-N-nitroso guanidine. Mutants were selected that had either smaller colonies at 37 C or temperature sensitivity for growth at 41 C. Four small-colony mutants and 2 temperature-sensitive mutants were studied. All the mutants were...
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