Article
RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis.
Molecular immunology - 1 Oct 2012
Pavkova Goldbergova Monika, Lipkova Jolana, Pavek Nikolas, Gatterova Jindra, Vasku Anna, Soucek Miroslav, Nemec Petr
Abstract excerpt
The MCP-1/CCL2 as well as RANTES/CCL5 chemokines are potent chemoattractants involved in immunoregulatory and inflammatory processes of rheumatoid arthritis. Recent studies demonstrated elevated levels of MCP-1 and RANTES in plasma, synovial fluid, and the synovial tissue of patients with RA. To examine the relationship among MCP-1 and RANTES single nucleotide polymorphisms and circulating levels and rheumatoid...
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