Article
RANTES: a genetic risk marker for multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2004
Gade-Andavolu Radhika, Comings David E, MacMurray James, Vuthoori Ravi K, Tourtellotte Wallace W, Nagra Rashed M, Cone Lawrence A
Abstract excerpt
UNLABELLED: Regulated upon activation, normal T-cell expressed and secreted (RANTES) is a beta-chemokine and has been detected in brain lesions of multiple sclerosis (MS) patients. Considering its potential role in MS, we screened two functional polymorphisms in the proximal promoter region of the RANTES in MS patients versus controls. METHODS: We examined 140 postmortem brain samples from subjects with a primary...
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