Article
Association study of genetic variants of pro-inflammatory chemokine and cytokine genes in systemic lupus erythematosus.
BMC medical genetics - 23 May 2006
Sánchez Elena, Sabio José M, Callejas José L, de Ramón Enrique, Garcia-Portales Rosa, García-Hernández Francisco J, Jiménez-Alonso Juan, González-Escribano Ma Francisca, Martín Javier, Koeleman Bobby P
Abstract excerpt
BACKGROUND: Several lines of evidence suggest that chemokines and cytokines play an important role in the inflammatory development and progression of systemic lupus erythematosus. The aim of this study was to evaluate the relevance of functional genetic variations of RANTES, IL-8, IL-1alpha, and...
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