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Article

Prognostic significance of the genetic variant of lymphotoxin alpha (p.Thr60Asn) in egyptian patients with advanced hepatocellular carcinoma.

Molecular biology reports - 1 May 2023

Alhelf Maha, Shoaib Rasha M S, Elsaid Afaf, Bastawy Nermeen, Elbeltagy Nanis S, Salem Eman T, Refaat Sherif, Abuelnadar Eman H

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide in terms of mortality, and susceptibility is attributed to genetic, lifestyle, and environmental factors. Lymphotoxin alpha (LTA) has a crucial role in communicating the lymphocytes with stromal cells and provoking cytotoxic effects on the cancer cells. There are no reports on the contribution of the LTA (c.179 C>A;...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36929286
DOI: 10.1007/s11033-023-08281-z
PMCID: PMC10147750

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