Article
Lymphotoxin-alpha polymorphisms and presence of cancer in 1,536 consecutive autopsy cases.
BMC cancer - 13 Aug 2008
Takei Kako, Ikeda Shinobu, Arai Tomio, Tanaka Noriko, Muramatsu Masaaki, Sawabe Motoji
Abstract excerpt
BACKGROUND: Lymphotoxin-alpha (LTA) is a pro-inflammatory cytokine with anti-tumor activity. The objective of this study was to determine whether LTA polymorphisms influence the presence of cancer. METHODS: LTA polymorphisms C804A (rs1041981, T60N) and T495C (rs2229094, C13R) were determined in 1...
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