Article
Genetic variations in CTLA-4, TNF-α, and LTA and susceptibility to T-cell lymphoma in a Chinese population.
Cancer epidemiology - 1 Dec 2013
Liu Jie, Liu Jing, Song Bao, Wang Ti, Liu Yuhong, Hao Jing, Yu Jinming
Abstract excerpt
OBJECTIVE: T-cell lymphoma is a highly aggressive malignant lymphoma that is rare in Caucasians but relatively common in Asian populations. Factors regulating T-cell proliferation and function may play an important role in the pathogenesis of T-cell lymphoma. METHODS: A total of 8 single nucleotide polymorphisms in cytotoxic T lymphocyte antigen-4 (CTLA-4), tumor necrosis factor-α (TNF-α), and lymphotoxin-α (LTA)...
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