Article
Increased risk for gastric cancer in carriers of the lymphotoxin-α+252G variant infected by Helicobacter pylori.
Genetic testing and molecular biomarkers - 1 Jan 2012
He Bangshun, Pan Yuqin, Xu Yeqiong, Nie Zhenlin, Chen Liping, Gu Ling, Wang Shukui
Abstract excerpt
The objective of this study is to determine whether polymorphisms in the lymphotoxin-α (LTA) and interleukin-10 (IL-10) genes were associated with gastric cancer (GC) in a Chinese population. One hundred ninety-six patients with GC and 248 healthy individuals were enrolled in this case-control study. The LTA 252G was associated with an increased risk of GC, with an adjusted odds ratio (OR) of 1.74 (95% confidence...
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