Article
SNP-set analysis replicates acute lung injury genetic risk factors.
BMC medical genetics - 28 Jun 2012
Meyer Nuala J, Daye Zhongyin John, Rushefski Melanie, Aplenc Richard, Lanken Paul N, Shashaty Michael G S, Christie Jason D, Feng Rui
Abstract excerpt
BACKGROUND: We used a gene - based replication strategy to test the reproducibility of prior acute lung injury (ALI) candidate gene associations. METHODS: We phenotyped 474 patients from a prospective severe trauma cohort study for ALI. Genomic DNA from subjects' blood was genotyped using the IBC...
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