Article
[Study on phenotypical activity of isoenzyme CYP3A4 in children].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Jan 2012
Kantemirova B I, Chernysheva A Kh, Starodubtsev A K, Sychev D A
Abstract excerpt
The urine levels of cortisol and 6-beta-hydroxycortisol in 30 healthy children were determined with high performance liquid chromatography. The activity of cytochrome P450 isoenzyme CYP3A4 was estimated by the ratio of 6-beta-hydroxycortisol and cortisol. Differences in the CYP3A4 activity depend...
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