Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Polymorhism of CYP17 gene and age of menarche].

Ginekologia polska - 1 Dec 2007

Kulik-Rechberger Beata, Skorupski Paweł, Bogusiewicz Michał, Miotła Paweł, Rechberger Tomasz

Abstract excerpt

OBJECTIVES: It is believed that the age of menarche may be related to polymorphisms in the genes involved in estrogen biosynthesis. A candidate gene is CYP 17 encoding cytochrome P450 c17alpha, which mediates activity of steroid 17-hydroxylase and 17,20-lyase. A single base-pair change (T-->C) in the promoter region of CYP 17 creates a polymorphic variant with an additional SP-1 transcription factor binding site....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Menarche
Share to Poland

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Steroid 17-alpha-Hydroxylase

Share to Adolescent

Share to Cytochrome P-450 CYP1A2

Share to Cytochrome P-450 Enzyme System

Source

Identifiers

PMID: 18411914

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Polymorhism of CYP17 gene and age of menarche].PMID 18411914Read ↗

Are CYP1A1, CYP17 and CYP1B1 mutation genes involved on girls with precocious puberty? A pilot study.Semantic proximity Read ↗

[Association between polymorphism of CYP17 gene and serum hormone concentrations in aged men].Semantic proximity Read ↗

Estrogen-metabolizing gene polymorphisms, but not estrogen receptor-alpha gene polymorphisms, are associated with the onset of menarche in healthy postmenopausal Japanese women.Semantic proximity Read ↗

CYP17 genotypes differ in salivary 17-beta estradiol levels: a study based on hormonal profiles from entire menstrual cycles.Semantic proximity Read ↗

The polymorphic locus rs314276 of the LIN28B gene is associated with the age of menarche in women of the Central Black Earth Region of RussiaSemantic proximity Read ↗

Association of polymorphisms of the oestrogen receptor alpha gene with the age of menarche.Semantic proximity Read ↗

[Correlation between CYP17 gene polymorphisms and female post adolescent acne in Han population in Hunan Province].Semantic proximity Read ↗

Investigations on the genetic polymorphism in the region of CYP17 gene encoding 5'-UTR in patients with polycystic ovarian syndrome.Semantic proximity Read ↗

Genetic polymorphisms of cytochrome P450cl7alpha (CYP17) and progesterone receptor genes (PROGINS) in the assessment of endometriosis risk.Semantic proximity Read ↗

Association of SHBG gene polymorphism with menarche.Semantic proximity Read ↗

The T/C polymorphism of the CYP17 gene and G/A polymorphism of the CYP19 gene in endometrial cancer.Semantic proximity Read ↗

[Puvll and Xbal gene polymorphisms of estrogen receptor alpha in children and young adults with cancer from north-eastern region of Poland].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.