Article
[Association of xenobiotic-metabolizing gene polymorphisms with childhood atopic diseases in Russian patients from the Republic of Bashkortostan].
Molekuliarnaia biologiia - 1 Jan 2000
Fedorova Iu Iu, Gra O A, Karunas A S, Khuzina A Kh, Ramazanova N N, Iuldasheva A A, Biktasheva A R, Etkina E I, Nasedkina T V, Goldenkova-Pavlova I V, Khusnutdinova E K
Abstract excerpt
Enzymes of biotransformation system involved in the metabolism of exogenous and endogenous compounds are effective mechanism of protection from negative environmental factors. Decreasing activity or insufficient synthesis of biotransformation system enzymes caused by genetic polymorphism form the risk of various complex diseases, including atopic. Using allele-specific hybridization on the biochip the frequencies...
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