Article
Mapping multiple QTL using linkage disequilibrium and linkage analysis information and multitrait data.
Genetics, selection, evolution : GSE - 1 Jan 2000
Meuwissen Theo H E, Goddard Mike E
Abstract excerpt
A multi-locus QTL mapping method is presented, which combines linkage and linkage disequilibrium (LD) information and uses multitrait data. The method assumed a putative QTL at the midpoint of each marker bracket. Whether the putative QTL had an effect or not was sampled using Markov chain Monte Carlo (MCMC) methods. The method was tested in dairy cattle data on chromosome 14 where the DGAT1 gene was known to be...
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