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Article

Effects of phenotypes in heterocyclic aromatic amine (HCA) metabolism-related genes on the association of HCA intake with the risk of colorectal adenomas.

Cancer causes & control : CCC - 1 Sept 2012

Barbir Aline, Linseisen Jakob, Hermann Silke, Kaaks Rudolf, Teucher Birgit, Eichholzer Monika, Rohrmann Sabine

Abstract excerpt

BACKGROUND: Heterocyclic aromatic amines (HCA), formed by high-temperature cooking of meat, are well-known risk factors for colorectal cancer (CRC). Enzymes metabolizing HCAs may influence the risk of CRC depending on the enzyme activity level. We aimed to assess effect modification by polymorphisms in the HCA-metabolizing genes on the association of HCA intake with colorectal adenoma (CRA) risk, which are...

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PMID: 22740027
DOI: 10.1007/s10552-012-0017-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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