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Article

Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2.

PLoS genetics - 1 Jan 2012

Bochkis Irina M, Schug Jonathan, Ye Diana Z, Kurinna Svitlana, Stratton Sabrina A, Barton Michelle C, Kaestner Klaus H

Abstract excerpt

Gene duplication is a powerful driver of evolution. Newly duplicated genes acquire new roles that are relevant to fitness, or they will be lost over time. A potential path to functional relevance is mutation of the coding sequence leading to the acquisition of novel biochemical properties, as ana...

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Identifiers

PMID: 22737085
DOI: 10.1371/journal.pgen.1002770
PMCID: PMC3380847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22737085-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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