Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Species-Specific Strategies Underlying Conserved Functions of Metabolic Transcription Factors

4 Feb 2011

Abstract excerpt

The winged helix protein FOXA2 and the nuclear receptor peroxisome proliferator-activated receptor-γ (PPARγ) are highly conserved, regionally expressed transcription factors (TFs) that regulate networks of genes controlling complex metabolic functions. Cistrome analysis for Foxa2 in mouse liver and PPARγ in mouse adipocytes has previously produced consensus-binding sites that are nearly identical to those used by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to FOXO transcription factor regulation
Share to Genetic Mapping and Diversity in Plants and Animals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21292830
DOI: 10.1210/me.2010-0454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Species-Specific Strategies Underlying Conserved Functions of Metabolic Transcription FactorsPMID 21292830Read ↗

Genome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2.Semantic proximity Read ↗

Tissue-specific transcriptional regulation has diverged significantly between human and mouse.Semantic proximity Read ↗

Meta-analysis of inter-species liver co-expression networks elucidates traits associated with common human diseases.Semantic proximity Read ↗

Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.Semantic proximity Read ↗

Multilevel integrative transcriptome analyses in humans and humanized mice define in vivo human lncRNA metabolic regulatorsSemantic proximity Read ↗

Conserved and species-specific transcription factor co-binding patterns drive divergent gene regulation in human and mouse.Semantic proximity Read ↗

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.Semantic proximity Read ↗

Genome-wide comparative analysis reveals human- mouse regulatory landscape and evolutionSemantic proximity Read ↗

Cross species comparison of C/EBPα and PPARγ profiles in mouse and human adipocytes reveals interdependent retention of binding sitesSemantic proximity Read ↗

Genomic Convergence in Hibernating Mammals Elucidates the Genetics of Metabolic Regulation in the HypothalamusSemantic proximity Read ↗

Genomic convergence in hibernating mammals elucidates the genetics of metabolic regulation in the hypothalamusSemantic proximity Read ↗

Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.