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Article

Stem cell factor-mediated wild-type KIT receptor activation is critical for gastrointestinal stromal tumor cell growth.

World journal of gastroenterology - 21 Jun 2012

Bai Chen-Guang, Hou Xiao-Wei, Wang Feng, Qiu Cen, Zhu Yan, Huang Ling, Zhao Jing, Xu Jing-Jing, Ma Da-Lie

Abstract excerpt

AIM: To clarify the biological role of stem cell factor (SCF)-mediated wild-type KIT receptor activation in gastrointestinal stromal tumor (GIST) growth. METHODS: The co-expression of wild-type KIT receptor and SCF was evaluated in 51 GIST samples using mutation analysis and immunohistochemistry, and the results were correlated with clinicopathological parameters, including the mitotic count, proliferative index...

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Source

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Identifiers

PMID: 22736916
DOI: 10.3748/wjg.v18.i23.2929
PMCID: PMC3380320

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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