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Article

Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma.

Cancer - 1 Jan 2013

Lee Joo Ho, Chung Young-Hwa, Kim Jeong A, Shim Ju Hyun, Lee Danbi, Lee Han Chu, Shin Eun-Soon, Yoon Jung Hwan, Kim Byung Ik, Bae Si Hyun, Koh Kwang Cheol, Park Neung-Hwa

Abstract excerpt

BACKGROUND: Sorafenib currently sets the new standard for advanced hepatocellular carcinoma (HCC). It has been suggested that Asian patients with HCC have increased susceptibility to hand-foot skin reaction (HFSR) related to sorafenib therapy. The authors investigated the association between sorafenib-induced HFSR and genetic polymorphisms in Korean patients with HCC. METHODS: For this prospective cohort study,...

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PMID: 22736425
DOI: 10.1002/cncr.27705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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