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Article

Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse model.

Journal of biomedical optics - 1 Jun 2012

Bista Rajan K, Uttam Shikhar, Hartman Douglas J, Qiu Wei, Yu Jian, Zhang Lin, Brand Randall E, Liu Yang

Abstract excerpt

The development of accurate and clinically applicable tools to assess cancer risk is essential to define candidates to undergo screening for early-stage cancers at a curable stage or provide a novel method to monitor chemoprevention treatments. With the use of our recently developed optical technology--spatial-domain low-coherence quantitative phase microscopy (SL-QPM), we have derived a novel optical biomarker...

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Identifiers

PMID: 22734770
DOI: 10.1117/1.JBO.17.6.066014
PMCID: PMC3382352

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Source receipt: pubmed, retrieved 7 Sept 2026.

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