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Article

Anticonvulsant valproate reduces seizure-susceptibility in mutant Drosophila.

Brain research - 20 Dec 2002

Kuebler Daniel, Tanouye Mark

Abstract excerpt

Despite the frequency of seizure disorders in the human population, the genetic basis for these defects remains largely unclear. Currently, only a fraction of the epilepsies can be linked conclusively to a genetic determinant. In addition, a significant number of epileptics do not respond to the current anticonvulsant therapies. We have turned to Drosophila as a model to address these problems and have identified...

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Identifiers

PMID: 12468028
DOI: 10.1016/s0006-8993(02)03431-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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