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Article

Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases.

Haematologica - 1 Dec 2012

Schnittger Susanne, Bacher Ulrike, Alpermann Tamara, Reiter Andreas, Ulke Madlen, Dicker Frank, Eder Christiane, Kohlmann Alexander, Grossmann Vera, Kowarsch Andreas, Kern Wolfgang, Haferlach Claudia, Haferlach Torsten

Abstract excerpt

We analyzed 636 patients with diverse myeloproliferative neoplasms or myelodysplastic/myeloproliferative neoplasms for mutations of the Casitas B-cell lymphoma gene (CBL(mut)) in exons 8 and 9 and performed correlations to other genetic alterations. CBL(mut) were detected in 63 of 636 (9.9%) of these selected patients. CBL(mut) were more frequent in myelodysplastic/myeloproliferative neoplasms than...

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Identifiers

PMID: 22733026
DOI: 10.3324/haematol.2012.065375
PMCID: PMC3685285

Genes

CBL
JAK2
TET2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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