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Article

The effect of colchicine on pyrin and pyrin interacting proteins.

Journal of cellular biochemistry - 1 Nov 2012

Taskiran Ekim Z, Cetinkaya Arda, Balci-Peynircioglu Banu, Akkaya Yeliz Z, Yilmaz Engin

Abstract excerpt

MEFV which encodes pyrin, cause familial Mediterranean fever (FMF), the most common auto-inflammatory disease. Pyrin is believed to be a regulator of inflammation, though the nature of this regulatory activity remains to be identified. Prophylactic treatment with colchicine, a microtubule toxin, has had a remarkable effect on disease progression and outcome. It has been thought that, inhibition of microtubule...

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Source

Identifiers

PMID: 22730186
DOI: 10.1002/jcb.24231

Genes

MEFV
PSTPIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The effect of colchicine on pyrin and pyrin interacting proteins.PMID 22730186Read ↗

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