Article
An heteroduplex mobility analysis assay based on capillary electrophoresis for the study of HCV quasispecies.
Journal of virological methods - 9 Jun 2003
Rossi Laura, Leveri Michela, Marinelli Daniela, Belli Luca, Civardi Emilio, Silini Enrico M
Abstract excerpt
The quasispecies nature of the hepatitis C virus (HCV) genome is central to the transmission, persistence and pathogenesis of the infection. Heteroduplex mobility analysis (HMA) is a simple and an inexpensive technique for the qualitative and quantitative analysis of genetic variation of viral quasispecies. An original HMA for the HVR1 region of HCV was developed, based on a semi-automated, non-radioactive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
