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Article

Autophagosome formation can be achieved in the absence of Atg18 by expressing engineered PAS-targeted Atg2.

FEBS letters - 30 Jul 2012

Kobayashi Takafumi, Suzuki Kuninori, Ohsumi Yoshinori

Abstract excerpt

The Atg2-Atg18 complex is essential for autophagosome formation in Saccharomyces cerevisiae. In this paper, we show that partial induction of autophagy can proceed in cells expressing engineered variants of Atg2 capable of localizing to the pre-autophagosomal structure (PAS) in the absence of Atg...

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Identifiers

PMID: 22728243
DOI: 10.1016/j.febslet.2012.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22728243-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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