Article
A role for Atg8-PE deconjugation in autophagosome biogenesis.
Autophagy - 1 May 2012
Nair Usha, Yen Wei-Lien, Mari Muriel, Cao Yang, Xie Zhiping, Baba Misuzu, Reggiori Fulvio, Klionsky Daniel J
Abstract excerpt
Formation of the autophagosome is likely the most complex step of macroautophagy, and indeed it is the morphological and functional hallmark of this process; accordingly, it is critical to understand the corresponding molecular mechanism. Atg8 is the only known autophagy-related (Atg) protein required for autophagosome formation that remains associated with the completed sequestering vesicle. Approximately...
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