Article
Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae.
Molecular biology of the cell - 1 Jul 2010
Geng Jiefei, Nair Usha, Yasumura-Yorimitsu Kyoko, Klionsky Daniel J
Abstract excerpt
In eukaryotic cells, autophagy mediates the degradation of cytosolic contents in response to environmental change. Genetic analyses in fungi have identified over 30 autophagy-related (ATG) genes and provide substantial insight into the molecular mechanism of this process. However, one essential issue that has not been resolved is the origin of the lipids that form the autophagosome, the sequestering vesicle that...
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