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Article

Insights into X chromosome inactivation from studies of species variation, DNA methylation and replication, and vice versa.

Genetical research - 1 Jan 2000

Migeon B R

Abstract excerpt

I am indebted to Mary Lyon as her X-inactivation hypothesis stimulated my mentor, Barton Childs, and in turn, myself, to think about the consequences of X-inactivation in heterozygous females. I often reread her original papers setting forth the single active X hypothesis, and still marvel at the concise and compelling exposition of the hypothesis and the logical predictions which seemed prophetic at my first...

Topics

Animals
DNA
DNA Replication
Dinucleoside Phosphates
Dosage Compensation, Genetic
Embryonic and Fetal Development
Female
Genetic Variation
Humans
Male
Methylation
Species Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

X Chromosome

Source

Identifiers

PMID: 2272520
DOI: 10.1017/s0016672300035151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2272520-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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