Effects of -1018G>A polymorphism of HRH2 (rs2607474) on the severity of gastric mucosal atrophy.

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Article

Effects of -1018G>A polymorphism of HRH2 (rs2607474) on the severity of gastric mucosal atrophy.

Journal of gastrointestinal and liver diseases : JGLD - 1 Jun 2012

Yamada Hideto, Tahara Tomomitsu, Shiroeda Hisakazu, Hayashi Ranji, Saito Takashi, Nakamura Masakatsu, Tsuchishima Mutsumi, Tsutsumi Mikihiro, Shibata Tomoyuki, Arisawa Tomiyasu

Abstract excerpt

BACKGROUND AND AIM: Histamine plays important physiological roles in upper gastrointestinal tract and acts via the H2 receptor. A polymorphism -1018 G>A (rs2067474) was identified in an enhancer element of the HRH2 promoter. We attempted to clarify the associations of this polymorphism with the p...

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Identifiers

PMID: 22720301

Genes

HRH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22720301-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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