PRKCH gene polymorphism is associated with the risk of severe gastric atrophy.

doi:10.1007/s10120-009-0542-7

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

PRKCH gene polymorphism is associated with the risk of severe gastric atrophy.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Jun 2010

Goto Yasuyuki, Hishida Asahi, Matsuo Keitaro, Tajima Kazuo, Morita Emi, Naito Mariko, Wakai Kenji, Hamajima Nobuyuki

Abstract excerpt

BACKGROUND: Individuals infected with Helicobacter pylori do not necessarily develop gastric atrophy (GA) and gastric cancer (GC). Several factors, including genetic polymorphism, can regulate the development of GA and GC. A G/A single nucleotide polymorphism (rs3783799) of the PRKCH gene, which encodes the eta isozyme of protein kinase C (PKCeta), has been reported to be a tag single nucleotide polymorphism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gastritis, Atrophic

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Protein Kinase C

Share to Severity of Illness Index

Share to Stomach Neoplasms

Source

Open in PubMed

Identifiers

PMID: 20602195
DOI: 10.1007/s10120-009-0542-7

Genes

PRKCH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PRKCH gene polymorphism is associated with the risk of severe gastric atrophy.PMID 20602195Read ↗

Risk of gastric cancer is associated with PRKAA1 gene polymorphisms in Koreans.Semantic proximity Read ↗

Association of the AURKA and AURKC gene polymorphisms with an increased risk of gastric cancer.Semantic proximity Read ↗

Impact of pepsinogen C polymorphism on individual susceptibility to gastric cancer and its precancerous conditions in a Northeast Chinese population.Semantic proximity Read ↗

PGC TagSNP and its interaction with H. pylori and relation with gene expression in susceptibility to gastric carcinogenesis.Semantic proximity Read ↗

Association between common genetic variant of HRH2 and gastric cancer risk.Semantic proximity Read ↗

DNA repair polymorphisms and the risk of stomach adenocarcinoma and severe chronic gastritis in the EPIC-EURGAST study.Semantic proximity Read ↗

TLR1 and PRKAA1 Gene Polymorphisms in the Development of Atrophic Gastritis and Gastric CancerSemantic proximity Read ↗

Polymorphic rs9471643 and rs6458238 upregulate PGC transcription and protein expression in overdominant or dominant models.Semantic proximity Read ↗

ALDH2 and ADH1 genetic polymorphisms may contribute to the risk of gastric cancer: a meta-analysis.Semantic proximity Read ↗

Association between PRKAA1 rs13361707 T>C polymorphism and gastric cancer risk: Evidence based on a meta-analysis.Semantic proximity Read ↗

Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection: a study from northern India.Semantic proximity Read ↗

Are Helicobacter pylori highly cytotoxic genotypes and cardia gastric adenocarcinoma linked? Lessons from Iran.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.