Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A high-resolution view of genome-wide pneumococcal transformation.

PLoS pathogens - 1 Jan 2012

Croucher Nicholas J, Harris Simon R, Barquist Lars, Parkhill Julian, Bentley Stephen D

Abstract excerpt

Transformation is an important mechanism of microbial evolution through which bacteria have been observed to rapidly adapt in response to clinical interventions; examples include facilitating vaccine evasion and the development of penicillin resistance in the major respiratory pathogen Streptococcus pneumoniae. To characterise the process in detail, the genomes of 124 S. pneumoniae isolates produced through in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Biological Evolution
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Molecular Sequence Data

Share to Recombination, Genetic

Share to Streptococcus pneumoniae

Share to Transformation, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 22719250
DOI: 10.1371/journal.ppat.1002745
PMCID: PMC3375284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A high-resolution view of genome-wide pneumococcal transformation.PMID 22719250Read ↗

Evolution via recombination: Cell-to-cell contact facilitates larger recombination events in Streptococcus pneumoniae.Semantic proximity Read ↗

Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration eventsSemantic proximity Read ↗

Mechanisms of genome evolution of Streptococcus.Semantic proximity Read ↗

Mechanisms and impact of genetic recombination in the evolution of <i>Streptococcus pneumoniae</i>Semantic proximity Read ↗

Regulation of natural genetic transformation and acquisition of transforming DNA in Streptococcus pneumoniaeSemantic proximity Read ↗

Disentangling competence for genetic transformation and virulence in Streptococcus pneumoniae.Semantic proximity Read ↗

Shaping a bacterial genome by large chromosomal replacements, the evolutionary history of Streptococcus agalactiae.Semantic proximity Read ↗

Heterogeneity in the Frequency and Characteristics of Homologous Recombination in Pneumococcal EvolutionSemantic proximity Read ↗

Population genetics and evolution of the pan-genome of Streptococcus pneumoniae.Semantic proximity Read ↗

Diversification of bacterial genome content through distinct mechanisms over different timescales.Semantic proximity Read ↗

Transformation of Natural Genetic Variation into Haemophilus Influenzae GenomesSemantic proximity Read ↗

The Role of Interspecies recombinations in the evolution of antibiotic-resistant pneumococciSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.