Article
Diversification of bacterial genome content through distinct mechanisms over different timescales.
Nature communications - 19 Nov 2014
Croucher Nicholas J, Coupland Paul G, Stevenson Abbie E, Callendrello Alanna, Bentley Stephen D, Hanage William P
Abstract excerpt
Bacterial populations often consist of multiple co-circulating lineages. Determining how such population structures arise requires understanding what drives bacterial diversification. Using 616 systematically sampled genomes, we show that Streptococcus pneumoniae lineages are typically characterized by combinations of infrequently transferred stable genomic islands: those moving primarily through transformation,...
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