Article
Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration events
2020-03-16
Abstract excerpt
The rapid spread of antimicrobial resistance and vaccine escape in the opportunistic human pathogen Streptococcus pneumoniae can be largely attributed to competence-induced transformation. To better understand the dynamics of competence-induced transformation, we studied this process at the single-cell level. We show that within isogenic populations, all cells become naturally competent and bind exogenous DNA. In...
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Identifiers and source
- Literature Corpus work
- 39cd5f6e-76f6-5f54-943a-b1a329277d47
- DOI
- 10.1101/2020.03.15.992354