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Transformation of Natural Genetic Variation into Haemophilus Influenzae Genomes

28 Jul 2011

Abstract excerpt

Many bacteria are able to efficiently bind and take up double-stranded DNA fragments, and the resulting natural transformation shapes bacterial genomes, transmits antibiotic resistance, and allows escape from immune surveillance. The genomes of many competent pathogens show evidence of extensive historical recombination between lineages, but the actual recombination events have not been well characterized. We...

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PMID: 21829353
DOI: 10.1371/journal.ppat.1002151

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