Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise.

Abstract excerpt

Hereditary keratin disorders of the skin and its appendages comprise a large group of clinically heterogeneous disfiguring blistering and ichthyotic diseases, primarily characterized by the loss of tissue integrity, blistering and hyperkeratosis in severely affected tissues. Pathogenic mutations in keratins cause these afflictions. Typically, these mutations in concert with characteristic features have formed the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Keratins
• Share to MAP Kinase Signaling System