Article
Syndromic epidermal differentiation disorders: a new classification toward pathogenesis-based therapy.
The British journal of dermatology - 18 Sept 2025
Paller Amy S, Teng Joyce, Mazereeuw-Hautier Juliette, Hernández-Martín Ángela, Granier Tournier Céline, Hovnanian Alain, Aldwin-Easton Mandy, Tadini Gianluca, Schwartz Janice, Sprecher Eli, Malovitski Kiril, Ishida-Yamamoto Akemi, Choate Keith, Akiyama Masashi, O'Toole Edel A, Fischer Judith, Bodemer Christine, Gostynski Antoni, Schmuth Matthias
Abstract excerpt
Since the 2010 classification of ichthyoses, our understanding of hereditary epidermal differentiation disorders (EDDs) has markedly increased, allowing for consideration of new therapeutic targets based on disease pathogenesis. A new gene- and protein product function-based classification focuses on shared mechanisms of disease pathogenesis, with the possibility that grouped disorders may respond similarly to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.