Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Posttranslational modifications of keratins and their associated proteins as therapeutic targets in keratin diseases.

Current opinion in cell biology - 1 Dec 2023

Li Pei, Rietscher Katrin, Jopp Henriette, Magin Thomas M, Omary M Bishr

Abstract excerpt

The keratin cytoskeleton protects epithelia against mechanical, nonmechanical, and physical stresses, and participates in multiple signaling pathways that regulate cell integrity and resilience. Keratin gene mutations cause multiple rare monoallelic epithelial diseases termed keratinopathies, including the skin diseases Epidermolysis Bullosa Simplex (EBS) and Pachyonychia Congenita (PC), with limited available...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeleton
Share to Epidermolysis Bullosa Simplex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Keratins

Share to Mutation

Share to Nail Diseases and Treatments

Share to Protein Processing, Post-Translational

Share to Silk-based biomaterials and applications

Share to Skin and Cellular Biology Research

Source

Identifiers

PMID: 37925932
DOI: 10.1016/j.ceb.2023.102264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Posttranslational modifications of keratins and their associated proteins as therapeutic targets in keratin diseases.PMID 37925932Read ↗

Keratins and skin disease.Semantic proximity Read ↗

Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise.Semantic proximity Read ↗

Keratins and their associated skin disorders.Semantic proximity Read ↗

The molecular basis of human keratin disorders.Semantic proximity Read ↗

Keratins in health and disease.Semantic proximity Read ↗

Treatment of keratinocytes with 4-phenylbutyrate in epidermolysis bullosa: Lessons for therapies in keratin disordersSemantic proximity Read ↗

Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex.Semantic proximity Read ↗

Keratin gene mutations in disorders of human skin and its appendages.Semantic proximity Read ↗

Significance of stress keratin expression in normal and diseased epitheliaSemantic proximity Read ↗

A cell-based drug discovery assay identifies inhibition of cell stress responses as a new approach to treatment of epidermolysis bullosa simplex.Semantic proximity Read ↗

[Keratin diseases].Semantic proximity Read ↗

Keratin function in skin epithelia: a broadening palette with surprising shades.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.