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Article

Keratin disorders: from gene to therapy.

Human molecular genetics - 15 Oct 2011

McLean W H Irwin, Moore C B Tara

Abstract excerpt

The term 'keratin' is generally accepted to refer to the epithelial keratins of soft and hard epithelial tissues such as: skin, cornea, hair and nail. Since their initial characterization, the total number of mammalian keratins has increased to 54, including 28 type I and 26 type II keratins. Inherited defects that weaken the keratin load-bearing cytoskeleton produce phenotypes characterized by fragility of...

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Identifiers

PMID: 21890491
DOI: 10.1093/hmg/ddr379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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