Article
LEPR c.668A>G polymorphism in a cohort of Sri Lankan women with pre-eclampsia / pregnancy induced hypertension: a case control study.
BMC research notes - 19 Jun 2012
Tennekoon Kamani Hemamala, Indika Wijesekara Liyanage, Sugathadasa Rohan, Karunanayake Eric Hamilton, Kumarasiri Jayalath, Wijesundera Ajita
Abstract excerpt
BACKGROUND: Leptin is known to be elevated in pre-eclampsia/ pregnancy induced hypertension (PE/PIH). However the reports on the association of leptin receptor (LEPR) c.668A>G polymorphism with PE/PIH are inconsistent. FINDINGS: LEPR c.668A>G polymorphism was studied in a cohort of women with PE/PIH (N = 61) and normotensive pregnancies (N = 40) by polymerase chain reaction / restriction fragment length...
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