Article
Association of -2548 G/A polymorphism in the leptin gene with preeclampsia/pregnancy-induced hypertension.
Hypertension in pregnancy - 1 Jan 2010
Sugathadasa B H K R, Tennekoon K H, Karunanayake E H, Kumarasiri J M, Wijesundere A P D S
Abstract excerpt
OBJECTIVES: To investigate −2548 G/A polymorphism of LEP gene, plasma leptin and soluble leptin receptor in preeclampsia/pregnancy induced hypertension. METHODS: Sixty-two patients and 63 controls (normal pregnancies) studied in the third trimester. Leptin and soluble leptin receptor measured by enzyme immunosorbent assay and −2548 G/A polymorphism by polymerase chain reaction followed by restriction enzyme...
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